New Insights in Anorexia Nervosa - Université Paris Descartes (Paris 5) Accéder directement au contenu
Article Dans Une Revue Frontiers in Neuroscience Année : 2016

New Insights in Anorexia Nervosa

Résumé

Anorexia nervosa (AN) is classically defined as a condition in which an abnormally low body weight is associated with an intense fear of gaining weight and distorted cognitions regarding weight, shape, and drive for thinness. This article reviews recent evidences from physiology, genetics, epigenetics, and brain imaging which allow to consider AN as an abnormality of reward pathways or an attempt to preserve mental homeostasis. Special emphasis is put on ghrelino-resistance and the importance of orexigenic peptides of the lateral hypothalamus, the gut microbiota and a dysimmune disorder of neuropeptide signaling. Physiological processes, secondary to underlying, and premorbid vulnerability factors—the “pondero-nutritional-feeding basements”- are also discussed.
Fichier principal
Vignette du fichier
fnins-10-00256.pdf (3.37 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-02295593 , version 1 (01-04-2020)

Licence

Paternité

Identifiants

Citer

Philip Gorwood, Corinne Blanchet-Collet, Nicolas Chartrel, Jeanne Duclos, Pierre Dechelotte, et al.. New Insights in Anorexia Nervosa. Frontiers in Neuroscience, 2016, 10, ⟨10.3389/fnins.2016.00256⟩. ⟨hal-02295593⟩
194 Consultations
339 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More